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Ferret domestication began over 2,500 years ago, likely from the European polecat. Initially bred for hunting purposes, particularly rabbit control, ferrets were valued for their slender bodies and agility in burrows. Over time, humans selectively bred ferrets for temperament and adaptability, gradually shaping them into more docile companions. By the Middle Ages, ferrets were common throughout Europe, used not only for hunting but also as pets by nobility. Their domestication involved both physical and behavioral changes, such as reduced aggression and increased tolerance of human interaction. In modern times, ferrets are fully domesticated and thrive in household environments, requiring socialization, mental stimulation, and proper care. Despite their playful and mischievous nature, domesticated ferrets depend on humans for survival. Their domestication story highlights the long-standing relationship between humans and animals, driven by utility and companionship. Today, ferrets are cherished pets, known for their intelligence, curiosity, and energetic personalities.